Milam 7.5mg Tablet

Uses of Milam 7.5mg Tablet

• Conscious Sedation

How does Milam 7.5mg Tablet work?

Milam 7.5mg Tablet works by acting on certain receptors in the brain called GABA receptors, which cause the release of a neurotransmitter called GABA that transmits messages between the nerve cells. Hence, Milam 7.5mg Tablet helps stabilize the altered electrical activity of nerve cells in the brain to induce complete loss of consciousness and for sedation before the surgical or diagnostic procedure.

Side Effects of Milam 7.5mg Tablet

Common side effects include drowsiness, disorientation, tiredness, headache, and muscular weakness. These side effects typically diminish with repeated dosing. Parenteral administration of Milam 7.5 may lead to changes in vital signs, such as respiratory depression, apnea, blood pressure alterations, and pulse rate variations.

Quick Suggestions:

• The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor
• It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
• Avoid consuming alcohol as it may increase dizziness and drowsiness.
• Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremors, and confusion.

Indication of Milam 7.5mg Tablet

Milam 7.5 is a prescription sedative used to alleviate anxiety and muscle tension before diagnostic or therapeutic procedures. It is administered as a nasal spray under the supervision of a healthcare professional or after consulting with a doctor. This sedative helps patients feel more comfortable during investigations, minor surgeries, dental procedures, and similar medical interventions.

Pharmacology

Milam 7.5 belongs to the benzodiazepine class of drugs and works by enhancing the activity of gamma-aminobutyric acid (GABA), a neurotransmitter in the central nervous system. This action results in sedation, skeletal muscle relaxation, and reduced anxiety, and may induce sleep, anesthesia, or forgetfulness. Milam 7.5 binds to the GABA-A receptor's benzodiazepine site, increasing the frequency of chloride channel opening, thereby amplifying the effects of GABA.

Dosage & Administration of Milam 7.5mg Tablet

Oral dosage:

• Adults: 7.5-15 mg per day.
• Elderly and debilitated patients: 7.5 mg.

Premedication (prior to procedures):

• Adults: 15 mg administered 30-60 minutes before the procedure.

Intravenous infusion (for endoscopic or cardiovascular procedures):

• Initial dose (healthy adults): Approximately 2.5 mg.
• Initial dose (severe illness or elderly patients): 1-1.5 mg.

Intramuscular administration:

• Adults: 0.07-0.1 mg/kg body weight, typically 5 mg.
• Children: 0.15-0.20 mg/kg.
• Elderly and debilitated patients: 0.025-0.05 mg/kg.

Rectal administration (for preoperative sedation in children):

• Dose: 0.35-0.45 mg/kg, 20-30 minutes before general anesthesia induction.

Dose for anesthesia induction:

• 10-15 mg.

Interaction

Milam 7.5mg Tablet may interact with various medications, including neuroleptics, tranquilizers, antidepressants, sleep-inducing drugs, analgesics, anesthetics, antipsychotics, anxiolytics, antiepileptic drugs, and sedative antihistamines, potentially enhancing their effects.

Contraindications

Milam 7.5mg Tablet should not be administered to individuals with severe respiratory insufficiency, severe hepatic insufficiency, myasthenia gravis, sleep apnea syndrome, or known hypersensitivity to benzodiazepines or any component of the medication.

Pregnancy & Lactation

Milam 7.5mg Tablet should be avoided during pregnancy unless there are no alternative options. It may transfer into breast milk, making it unsuitable for nursing women.

Precautions & Warnings

Here are some key points to keep in mind when taking Midazolam:

• Inform your doctor if you are allergic to Midazolam or any other medications.
• If you are pregnant or planning to become pregnant, discuss the use of Midazolam with your doctor.
• Midazolam may be present in breast milk, so avoid breastfeeding for 24 hours after taking it.
• Use Midazolam with caution in elderly patients, as there is a higher risk of bone fractures and falls.
• When administering Midazolam to children, ensure the dosage is adjusted appropriately.
• Avoid consuming alcohol while using Midazolam, as it can intensify the sedative effect.
• MIDAZOLAM may cause drowsiness, affect concentration, and impair coordination.
• Driving is prohibited if Midazolam affects you and causes drowsiness.

Additionally, avoid combining Midazolam with opioids, as it can increase the risk of breathing difficulties, drowsiness, or coma. However, if a healthcare professional advises concurrent use, the dose and duration should be limited and monitored closely.

Storage Conditions

Store Milam 7.5 in a cool, dry place, protected from light and moisture, and keep it out of the reach of children.